Monday, December 9, 2013

Stages of Wound Healing

There are 4 phases of wound healing:

  1. Hemostasis: Clotting sequence is activated, vasoconstriction, thrombin --> fibrinogen --> fibrin. 
  2. Inflammation: During this phase debris and bacteria are phagocytosed. Neutrophils then Monocyctes and Macrophages(approx 4 days after injury)  then
  3. Proliferation: Angiogensis, Collogen deposition, granulation tissue formation, epithelialization and wound contraction. 
  4. Remodeling: Occurs for about a year. Scar tissue regains about 2/3 or original strength but is never as strong. 

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